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About tirzepatide Tirzepatide is a once-weekly dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that integrates the actions of both incretins into a single novel molecule

Semaglutide (Wegovy / Ozempic) Semaglutide is a once-weekly GLP-1 injection thats been on the market longer and has the most real-world data behind it

10.1016/j.mod.2015.07.007 Mech

We know that management of overweight and obesity is one of the biggest challenges our health service is facing, with nearly two-thirds of adults either overweight or obese, said Helen Knight, the programme director in the centre for health technology evaluation at Nice