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(download PDF Summary of genome-wide association studies included in this study
CCT-deficient B cells stimulated with LPS triggered early activation of the unfolded protein response (UPR)-mediated splicing of Xbp-1, and impaired class switching, reducing antigen-specific IgG1 production while increasing IgM secretion upon antigen challenge ( Figure 3 )
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Colchicine is an ancient anti-inflammatory drug that has been used for different rheumatic and immune diseases for many years
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