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Fourthly, while the intestine is the dominant source of circulating serotonin, future studies will be required to determine whether intestinally derived serotonin is the mediator of metabolic and hormonal changes characteristic of PBH and whether neural signaling is required
"In our extension trials that the FDA studied, when people did stop these medications, they did see weight coming back on, in about 50 percent of people," DeSalvo said
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