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Its mechanism involves specific engagement of AMY1R and AMY3R in hindbrain and hypothalamic circuits that regulate energy homeostasis, leading to preferential fat mass reduction and altered hypothalamic gene expression profiles [2]
Pregnancy and breastfeeding represent absolute contraindications based on precautionary principles
every week up to 4 weeks
The dose is 20 units (0.2 mL) subcutaneously, once nightly, Monday through Friday
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