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La secrecin de GLP-1 sigue un patrn bifsico tras la ingesta de alimentos: una fase temprana que ocurre minutos despus de comer, mediada por seales neurales y hormonales, y una fase tarda ms prolongada cuando los nutrientes alcanzan directamente las clulas L del intestino distal
It is a genuine dose-related signal that regulators will examine, and it is not a feature of the licensed GLP-1 medicines available in the UK
Histochemistry 56(1):3744 Mommsen TP, Mojsov S (1998) Glucagon-like peptide-1 activates the adenylyl cyclase system in rockfish enterocytes and brain membranes
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