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RNA quantification and gene fusion calling RNA-seq reads were aligned with STAR (GRCh38, Gencode 42/Ensembl 108 splice junctions) using crisp_align and quantified with Kallisto through crisp_quant, before detecting gene fusions with crisp_codac
First, a significant portion of the mechanistic support is derived from preclinical studies that utilize preventive or early intervention paradigms, which may not accurately reflect clinical treatment scenarios
doi: 10.1001/jamainternmed.2018.2933 134 Perez-Montes DE OcaAPelliteroSPuig-DomingoM
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