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There is no physiological reason that trying tirzepatide would make semaglutide less effective if you return to it
The molecule is classified as a triple receptor agonist, which means it interacts with the glucagon like peptide 1 receptor (GLP 1R), glucose dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR)
To minimize potential digestive side effects, doctors may suggest starting with a lower dose of Ozempic or adjusting the dosage over time
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