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The present review provides (1) an overview in the pathophysiology of NAFLD, including the potential involvement of GLP-1 and glucagon, (2) an introduction to the currently available GLP-1RAs and (3) outlines the potential of emerging GLP-1RAs and GLP-1/glucagon receptor co-agonists in the treatment of NAFLD

Most studies have focused on the effect of SSTR5, whereas the effect of SSTR2 antagonism on glucose tolerance has barely been touched upon

Brittany: just a way to slow things down a little bit and then make those long-term outcomes

If full discontinuation proves unsuccessful after 8 weeks, PlexusDx offers alternative compounds (Tirzepatide, GLP-Squared dual-mechanism therapy) that may provide superior appetite control with lower doses or different mechanisms