In mice fed Se deficient diets, testicular atrophy, reduced diameter of the seminiferous tubules, osseous metaplasia, and reduced spermatogenic activity were observed: no mitotic activity in spermatogonia, reduced the number of spermatogenic cell lines (including stem cells, pachytene spermatocytes, spermatids, and maturing sperms), and higher rates of abnormal morphology of sperm were found without difference in chromosomal abnormalities in spermatocytes (85, 100)
In skin and tissue models, researchers investigate the influence of GHK-Cu on gene expression, collagen- and elastin-related pathways, oxidative stress and inflammation modulation
Weyer C, Bogardus C, Mott DM, Pratley RE
reported that gene polymorphism TM6SF2 rs58542926 is fully connected with susceptibility to malignancy liver