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HSPA2 is a testis-enriched HSP70 member that is mainly distributed in spermatocytes and spermatids, where it participates in spermatogenesis and contributes to the quality control of spermatid proteins
Proteomic analysis identified 156 DEPs, with glutathione metabolism being the most severely disrupted pathway
Prospective randomized clinical trials are essential to confirm these associations and establish causality, Wang said
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