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In Column 3 of Table 6 we show the result of a substantial increase of oxidative stress in the model to 5 times the normal level

At the same time, a sequentially targeted sonodynamic nanovaccine Stars NV not only can increase the local M1/M2 TAM ratio and tumor-infiltrating lymphocytes while decreasing Tregs, but also can enhance systemic immunity, increase peripheral CD4 + T and CD8 + T cells and ultimately extend the survival of mice (197)

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