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More recent preclinical work has examined GHK-Cu in rodent models of pulmonary fibrosis, silicosis and airway remodelling, with oxidative stress and inflammatory signalling as the reported endpoints

These include: nausea diarrhoea vomiting constipation abdominal discomfort or related gastrointestinal symptoms in some reports Published trial summaries have described these gastrointestinal events as dose-related and generally mild to moderate in severity