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More condensed mitochondrial cristae were observed in blood cells from ME/CFS patients, but the mitochondrial crista length, sise, shape, density, membrane potential, and enzymatic activities of the complexes inside the ETC remained intact (384)

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Liver normally clears vasodilators (nitric oxide) from portal blood

On the day of the assay, serial dilutions (7-fold dilutions, 7 concentrations per compound and one well containing only assay buffer) of test compounds were performed in duplicate in assay buffer to appropriate concentrations in 96-well plates (Greiner, U-shape #GR-650201) using a Biomek i7 liquid handler