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Int J pharmaceutics (2019) 572:118782
Pyo et al
This is particularly interesting because it demonstrates FOXO4-DRI's senolytic activity extends to endocrine tissues and can restore hormonal function, not just structural tissue integrity
Compared with ddY mice (a general-purpose outbred mouse strain), the activity of 3HAO was significantly increased in the CNS of epilepsy-prone EL mice (a genetic model of temporal lobe epilepsy) [61]
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