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Exploratory endpoints reported included changes from baseline to week 104 in glycemic category, antihypertensive medication use, and lipid-lowering medication use
Among approved drugs, tirzepatide (Mounjaro/Zepbound) produced the largest average weight loss in trials, about 20.9% over 72 weeks at the highest dose in SURMOUNT-1, ahead of semaglutide at roughly 14.9% over 68 weeks in STEP 1
& Rssner, S
Semaglutides kidney benefits have been seen in other studies
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