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Oral administration of aqueous garlic extract and S-allylcysteine has been reported to enhance apoptosis in an animal model of oral cancer (74, 75)
doi: 10.1016/j.neuropharm.2023.109603 36 ZhangHLiuYChengLMaXLuoX
Unlike -KG, abnormal accumulation of succinate and fumarate in tumor tissues represses PHD, thus reducing HIF1 hydrolysis, suppressing demethylation of DNA and histones, and promoting the occurrence and development of tumors (Cavalli and Heard, 2019)
Box breathing, quiet walks, journaling, or guided mindfulness can help shift the nervous system away from chronic alert mode
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