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if symptoms include chest pain, severe breathlessness, or thoughts of self-harm, seek immediate medical attention by calling 999 or NHS 111

The distribution of the continuous variables was assessed by ShapiroWilk normality test and normal probability plots

According to the Summary of Product Characteristics (SmPC) for paracetamol, hepatic impairment is not listed as an absolute contraindication, though caution and possible dose reduction are advised depending on the severity of liver disease