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Beta Blockers In HFpEF, beta-blockers are not recommended as a primary disease-modifying therapy but are supported by the 2022 ACC/AHA/HFSA guidelines for the management of comorbid conditions such as atrial fibrillation, hypertension, and ischemic heart disease (Class I recommendation for these indications, not HFpEF itself)
HR: 0.62, 95% CI: 0.460.84)
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