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By limiting MLC-2driven tight junction destabilization while simultaneously promoting epithelial regeneration, larazotide not only reinforces barrier structure but also supports mucosal recovery after injury
Plasma concentration of trimethylamine-N-Oxide and risk of gestational diabetes mellitus
The study was supported by the UTSW Clinical and Translational Science Award, the National Institutes of Health (1U54TR00236), the Texas Health Resource Clinical Scholar program, and the UTSW Nutrition & Obesity Research Center (NORC).
A few things worth flagging for clinical practice: GI effects (nausea, diarrhea, vomiting) are dose-related and largely manageable with slow titration starting at 2 mg rather than jumping to 4 mg helps
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