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Particularly, tumor growth under hypoxia or mitochondrial dysfunction relies almost exclusively on this reductive glutamine metabolism for lipid biosynthesis (Metallo et al., 2011)
HS usually emerges in adolescence and is recurrent (216)
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Given the large number of women for whom these drugs are currently prescribed, these findings are of immediate clinical relevance and they heighten the need to better understand and ultimately mitigate this heightened susceptibility
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