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In the kidney, we observed widespread disruption in energy metabolism and multiple molecules involved in glycolysis, gluconeogenesis, and the TCA cycle were depleted, indicating a more global disruption in energy metabolism than has been previously appreciated

May relate to blood pressure effects in sensitive individuals

Although these stages are presented as an orderly progression, clinically that is not always the case

Abdelkhalek NK, Ghazy EW, Abdel-Daim MM (2015) Pharmacodynamic interaction of Spirulina platensis and deltamethrin in freshwater fish Nile tilapia, Oreochromis niloticus: impact on lipid peroxidation and oxidative stress