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Dihydroartemisinin prevents dextran sodium sulphate-induced colitisthrough inhibition of the activation of NLRP3 inflammasome and p38 MAPK signaling

Anti-remodeling targets acting over regulating genes of the S100A1, like phospholamban-targeted shRNA, and antioxidant enzymes (e.g., CAT) are under preclinical evaluation for preventing pathological hypertrophy and fibrosis