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Patients should expect subtle rather than dramatic changes

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The pulse it produces is sharp but brief, which is the single biggest practical limitation compared to modern alternatives

The most frequently reported reactions include: Redness (erythema) at the application site Itching or a tingling/stinging sensation , especially on freshly exfoliated or compromised skin Dryness or mild flaking , sometimes related to the overall formulation rather than the peptide itself Temporary irritation when combined with strong actives These reactions typically resolve on their own or after reducing frequency of use