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Moreover, DSIP has demonstrated the capacity to attenuate sleep initiation latency and minimize nocturnal arousal in preclinical studies on laboratory models
Biomolecules 11 , 1348 (2021)
This makes S-Acetyl-L-glutathione a promising candidate for conditions involving impaired GSH synthesis, offering a significant advantage in medical research and treatment strategies focusing on oxidative stress and related disorders
A structure-based assignment of the glutathione activator site without transition-state analogues is much more difficult because of labile GSH interactions 2 that likely depend not only on the presence of the first glutathione moiety but also on conformational changes of the glutathionylated enzyme 3,12,37,44
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