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However, clinical trials in humans have demonstrated mixed results
The approval was based on two key Phase 3 randomized, double-blind, placebo-controlled trials (LIPO-010 and LIPO-011) enrolling a combined 816 patients
Where Semaglutide wins: its prescription-available in Canada, has the longest real-world safety record in this class, and is covered by some provincial drug benefit programs and private insurance plans
In the UK, some patients are supported to self-inject at home, but only after proper training and with medical oversight
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