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Chronic inflammation, however, impedes healing and causes progressive tissue damage
Disruptions in detoxification and mitochondrial function may also interfere with melatonin production and restful sleep cycles
This concentration-dependent effect is epitomized in energy metabolism during exercise, where a shift from white adipose tissue to intramuscular triglycerides as the primary fatty acid source occurs as blood lactate rises from 2 mM to 5 mM, demonstrating lactates role as a metabolic rheostat in real-time [148]
Glick, D., Barth, S
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