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One study in the The Journal of Allergy and Clinical Immunology found that some injected forms of B vitamins at higher doses, like B12, can be linked with an allergic reaction

Manifestations and etiologies of vitamin B12 deficiency in adults Vitamin B12 deficiency is relatively frequent in elderly patients, around 2 to more than 30% according to depending on the target population, the design and location of the studies, but is often unrecognized or not investigated because the clinical manifestations of vitamin B12 deficiency are subtle [5]