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Preclinical studies suggest this inhibition may protect against diet-induced weight gain and improve metabolic health

It should be noted that these findings do not imply that DPP-4 inhibitors are harmful in any way or that GLP-1 drugs are definitely beneficial for brain health.

Studies on -synuclein demonstrate that methionine residues near the N-terminus are more susceptible to copper-mediated oxidation than internal residues, with Met1 substitution decreasing Cu-peptide reduction potential by approximately 80 mV