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In animal studies, this change inhibits detoxification, depletes glutathione levels, and increases inflammation
* Correspondence: Hongyang Liu [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Indeed, previous studies indicate that Nfe2l2 , along with NRF2 target genes such as Gclc and Gclm , exhibits circadian oscillations in the lung, as well as kidney, and aorta (58, 59)
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