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Due to the rapid metabolism of lidocaine HCl, any condition affecting liver function may alter its kinetics, which can double the half-life in patients with liver dysfunction
The Honest Answer At normal therapeutic doses, supervised by a qualified doctor, with branded pharmaceutical-grade vials, the safety profile is reasonable
One such study, REALISE-DM, observed HbA1c reductions and weight loss after switching to semaglutide, with most patients tolerating the change well
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