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The disadvantage is that your starting dose of 0.25 mg requires drawing only 5 units, which is a very small amount that can be difficult to measure precisely on larger syringes
Results of two randomized placebo-controlled trials of liraglutide in patients with advanced systolic heart failure, with or without diabetes, failed to demonstrate benefit of liraglutide, and the trend in both trials was worse outcomes with liraglutide versus placebo
How long a medication lasts is always an important question, but when you're paying hundreds of dollars for a single pen, the idea of throwing away "perfectly good" medication feels downright wasteful
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