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Vitamin B12 supports energy metabolism, neurological function, and is commonly depleted in people taking metformin or following restrictive diets
indeed, if some studies showed that the hormone is able to significantly downregulate autophagy in different disease models 63,64,65 , other reports failed to confirm those findings, providing evidence for an enhancement of the autophagic process upon melatonin treatment 66,67,68
TMAO and Acute Coronary Syndrome (ACS) More than half of cardiovascular deaths are caused by ACS, and the main cardiovascular disorder causing these acute cardiovascular events is the development of atherosclerosis (24)
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