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This detoxification process prevents the formation of the toxic semiquinone radicals and ROS, which are formed by one-electron reduction

Laboratory investigations have reported measurable changes in nitric oxide related signaling markers, endothelial migration assays, fibroblast gene expression profiles, and cytoskeletal reorganization markers in cell culture and animal models

J Bacteriol 182(6):1722 Wolfram L, Bauerfeind P (2002) Conserved low-affinity nickel-binding amino acids are essential for the function of the nickel permease NixA of Helicobacter pylori

liposomal delivery may partially bypass the gastric-emptying effect