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Eli Lilly also developed retatrutide, a triple-hormone receptor agonist (GLP-1/GIP/glucagon) currently in late-stage trials, with interim data suggesting up to 24% weight reduction
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We also saw more reports of hypersensitivity-type reactions, such as urticaria, than we anticipated, which raises interesting questions about possible immune-related mechanisms. Researchers also calculated the proportional reporting ratio (PRR) comparing adverse event rates between GLP-1 receptor agonist and DPP-IV inhibitors
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