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In one, patients who lost 10.6% of their weight after 20 weeks of Wegovy were randomized to continue it or switch to placebo

At iThrive, we begin every longevity journey with a Root Cause Analysis that evaluates nutrition, metabolism, hormones, gut health, inflammation, and lifestyle before considering advanced interventions

Medications demonstrated strong short-term efficacy on core symptoms, while CBT contributed modest to strong, and sometimes long-lasting, improvements in functional impairments and executive skills when used as part of combination therapy

As a 2026 review noted, the original composition-of-matter patents "have likely expired reducing the commercial exclusivity that typically incentivizes industry-sponsored Phase II and III development" [13]