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GLP-1 medications work by targeting the brains appetite regulation centers and slowing down digestion, which promotes a feeling of fullness, or satiety

The L-cells are open-type triangular epithelial cells directly in contact with the lumen and neuro-vascular tissue and are accordingly stimulated by various nutrient, neural and endocrine factors

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The opening of the LTCC contributes to the positive inotropic effect of isoprenaline, and when this opening is impaired by nifedipine, the positive inotropic effect of isoprenaline can be diminished