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In a 6-month trial of rhGH in GH-deficient adults, liver fat fraction fell from a mean of 12.4% to 7.8% (P 30, type 2 diabetes, or alcohol use disorder, add a FibroScan or hepatic ultrasound to establish a steatosis baseline before initiating therapy
Tesamorelin produces a pulsatile, physiologically normal GH release
Two 68-week phase 3 trials, REDEFINE-1, investigating CagriSema in subjects with obesity but not T2D, and REDEFINE-2, for individuals with obesity and T2D, have recently been completed
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