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A recent study has demonstrated that liraglutide crosses the bloodbrain barrier, reaching the arcuate nucleus (ARC), where GLP-1-RAs stimulate neurons that regulate appetite and express POMC and cocaine- and amphetamine-regulated transcripts (CART)
For example, reduced plasma glutathione levels have been shown to represent an increased risk for cardiovascular disease, iv And the primary cause of the neurodegeneration that leads to Parkinsons disease
PMID 3656429
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