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Typical Protocol: Common research protocols use a loading phase of roughly 4-8 mg per week (split into 2-3 subcutaneous injections) for 4-6 weeks, followed by a maintenance phase of about 2-6 mg biweekly for another 4-8 weeks, with a full cycle running 8-14 weeks and at least 4 weeks off before repeating
(181) established a high-iron diet mouse model, demonstrating that iron overload significantly increases iron levels in serum, colonic tissue, and feces, and successfully induces colitis phenotypes and ferroptosis
Patients should not self-adjust insulin or sulfonylurea doses without clinical guidance
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