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Serious adverse effects have not been widely reported, but long-term safety data in humans is lacking
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And then I would point out that there seems to be something else going on regardless of the amount of B12 in the patients blood
When total B12 measurements are unreliable, your doctor may request additional tests such as holotranscobalamin (active B12), methylmalonic acid, or homocysteine to assess your true B12 status more accurately
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