The measurements in this study were taken from two voxels, positioned in two anatomically and functionally different parts of the ACC, its rostral portion, the pregenual ACC (pgACC) and in its dorsal portion, the dorsal ACC (dACC) [33]
The lethal dose in humans would be approximately 21,000mg for a 70kg person, making the 1-3mg daily doses used in typical protocols extremely safe from a toxicity standpoint
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Being mindful of these dietary triggers can meaningfully improve day-to-day comfort and adherence to treatment