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1 No dose adjustment is needed in patients who have renal toxicity (acetaminophen can also be toxic to the kidneys)
limiting instrumental adl or mild/moderate impact on age-appropriate normal daily activity (pediatric) Grade 2 Akathisia, CTCAE|Grade 2 Akathisia severe restlessness or increased motor activity
Anyone concerned about the side effect burden of GLP-1 agonists
The SELECT trial showed that Wegovys cardiovascular benefits emerged independently of weight loss, suggesting that GLP-1 receptor activation has direct effects on the heart and blood vessels beyond what weight loss alone provides
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