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and Jones, D.P., Encyclopedia of Stress , San Diego: Elsevier, 2007, vol
melanogaster that could conjugate 4-hydroxynonenal (4-HNE), an electrophilic end-product of lipid peroxidation [129]
46,47,48 Through an antioxidant cascade, melatonin metabolites such as N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK) further neutralize free radicals, protecting mitochondrial integrity, proteins, and DNA from oxidative destruction
125 Evidence of inconsistent quality suggest guggul supplementation may help improve the lipid profile, but better-designed trials are needed to clarify efficacy
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