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However, concerns persist regarding long-term adherence, cardiovascular risks, increased workload placed for the kidneys (renal strain), micronutrient deficiencies, and alterations in gut microbiota
Taken together, metformin may upregulate PKA signalling to exert its synergistic protective effects with liraglutide in both GLP-1R-dependent and -independent manners in PA-impaired endothelial cells
Biotech company CervoMed presented new data indicating that its oral neflamapimod treatment for dementia with Lewy bodies led to a significant reduction in widely used neurodegeneration biomarkers , including plasma glial fibrillary acidic protein and beta amyloid 42/40 ratio
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