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BMI 27 with weight-related conditions, such as: Type 2 diabetes or prediabetes Hypertension High cholesterol Sleep apnea Fatty liver disease (NAFLD) PCOS Insulin resistance Patients in this range may be candidates because GLP-1 medications act on pathways related to blood sugar, appetite, and metabolic regulation

As planned, the 36 MI cases and 69 non-MI controls were similar in age (median 50 and 49), race (about half black and half white), proportion of men (78% and 77%), CD4 count (median 536 and 616), and months with a viral load below 400 copies (median 2.8 and 2.5)

But for raw efficacy, metabolic transformation, and body recomposition, Retatrutide is the clear winner based on current evidence