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Clinical trials show it lowers blood sugar and A1C levels below 7% (the recommended amount) for a significant number of patients
They did however comment in their New England Journal of Medicine article that the affinity of lixisenatide for the GLP-1 receptor was up to four times greater than that of human GLP-1and there have been neuroprotective actions shown in animal models of Alzheimers disease. Together, I suspect these were likely strong rationales driving their choice of the use of Lixisenatide
They were often prescribed off-label by physicians in regenerative and longevity practices
Research has suggested the peptide to be selective in its mode of action
