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Activation of these signaling pathways promotes the secretion of gut-derived hormones such as glucagon-like peptide-1 (GLP-1), peptide YY (PYY), and serotonin
10.1038/nature05484 27 MurthyK
Accordingly, a study showed that GSTP1 could upregulate the STAT3 to promote distance tissue and lymphatic metastasis, indicating its regulatory role in signaling pathways related to metastatic processes (Wang et al
The research tests a theory that states the human body's GLP-1 pathways function within joint tissues to control joint inflammation that occurs during osteoarthritis and rheumatoid arthritis
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