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For compounded semaglutide, consistency and safety rely on choosing a trusted compounding pharmacy and receiving ongoing monitoring from a healthcare provider
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According to the MHRA/EMC SmPC for Wegovy, the most frequently reported gastrointestinal side effects include: Nausea the most common adverse effect, affecting approximately 44% of patients in clinical trials, typically most pronounced during dose escalation Diarrhoea reported in around 30% of patients, ranging from mild to moderate severity Constipation affecting approximately 24% of patients, related to slowed gut transit Vomiting occurring in roughly 24% of patients, often associated with nausea Abdominal pain or discomfort reported by approximately 20% of patients Dyspepsia (indigestion) affecting around 9% of patients Bloating and flatulence commonly reported but less precisely quantified in trials These side effects are dose-dependent , meaning they tend to be more pronounced at higher doses and during the escalation phase
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