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Cocaine and amphetamines (stimulants) All animal studies retrieved for stimulants misuse involved exendin-4 among GLP-1RAs and highlighted a reduction of cocaine and amphetamines intake and end effects (for example, increased locomotor activity) via modulation of dopaminergic transmission in areas including the nucleus accumbens and the ventral tegmental area 91,92,93,94,96,97,98,99,100,101,102,103,105 , as well as modulation of inflammatory mechanisms 104
mRS 2 was considered as unfavorable outcome
Some participants in the 4 mg dose group initiated treatment at a 2 mg dose, which they later escalated to 4 mg
2022) with GIP-driven improvements in lipid metabolism and energy expenditure (MacIsaac et al
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