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This tool will be most valuable not only for further understanding physiologic adaptations of the cellular redox potential but also for studying redox-related mechanisms of drug action and resistance and for comparing different redox-related methodological approaches
A modified IGF-1 peptide with a 13-residue extension and an Arg substitution at position 3, used to study growth-factor signalling in vitro
Chelators, like EDTA, DMPS and DMSA are free radical scavengers
From the early inklings of an incretin factor in the 1900s, through the molecular identification of GLP-1 in the 1980s, to the ingenious harnessing of a lizards venom peptide in the 1990s each chapter built the foundation for what is now a pillar of modern therapy for metabolic diseases
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